2025
Efficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis
Chow R, Basu A, Kaur J, Hui D, Im J, Prsic E, Boldt G, Lock M, Eng L, Ng T, Zimmermann C, Scotte F. Efficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis. Supportive Care In Cancer 2025, 33: 193. PMID: 39953210, PMCID: PMC11828838, DOI: 10.1007/s00520-025-09251-w.Peer-Reviewed Original ResearchConceptsChemotherapy-induced nausea and vomitingEfficacy of cannabinoidsTHC:CBDMeta-analysisPrevention of chemotherapy-induced nausea and vomitingProphylaxis of chemotherapy-induced nausea and vomitingChemotherapy-induced nausea and vomiting controlControlled trialsCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsRegister of Controlled TrialsNausea and vomitingChemotherapy-induced nauseaMethodsA literature searchCochrane Central RegisterComplete responseRandomized controlled trialsNo vomitingAdjunctive therapyRescue medicationAntiemetic regimensComposite endpointSubgroup analysisCannabinoidSecondary prevention
2024
Multi-day vs single-day dexamethasone for the prophylaxis of chemotherapy-induced nausea and vomiting: systematic review and meta-analysis
Chow R, Celio L, Im J, Caini S, Eng L, Prsic E, Scotté F, Aapro M. Multi-day vs single-day dexamethasone for the prophylaxis of chemotherapy-induced nausea and vomiting: systematic review and meta-analysis. Supportive Care In Cancer 2024, 32: 736. PMID: 39432169, DOI: 10.1007/s00520-024-08934-0.Peer-Reviewed Original ResearchConceptsDexamethasone-sparing regimenChemotherapy-induced nausea and vomitingModerately emetogenic chemotherapyHighly emetogenic chemotherapyRandomized controlled trialsComplete responseMeta-analysisEmetogenic chemotherapyNo vomitingRescue medicationProphylaxis of chemotherapy-induced nausea and vomitingSystematic reviewSchedule of dexamethasoneNausea and vomitingChemotherapy-induced nauseaResultsTen trialsAntiemetic regimenCumulative meta-analysisEffect estimatesSafety profileComprehensive systematic reviewMethodsOvid MEDLINERegimensAdult cancer patientsCancer patients
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